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Symbol
Name
ID
Prkaca
protein kinase, cAMP dependent, catalytic, alpha
MGI:97592
Phenotype annotations related to endocrine/exocrine glands
Darker colors indicate more annotations
Human Phenotypes
Diabetes mellitus
Pancreatitis
Decreased circulating ACTH concentration
Decreased circulating dehydroepiandrosterone concentration
Increased serum testosterone level
Increased circulating cortisol level
Primary hypercortisolism
Paradoxical increased cortisol secretion on dexamethasone suppression test
Adrenal hyperplasia
Pigmented micronodular adrenocortical disease
Increased urinary cortisol level
Disease(s) Associated with PRKACA
primary pigmented nodular adrenocortical disease

Mouse Phenotypes
decreased insulin secretion
Availability Mouse Genotype
Prkacatm3Gsm/Prkacatm3Gsm
Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+  (conditional)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory